| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3198861 | Journal of Allergy and Clinical Immunology | 2011 | 12 Pages |
Abstract
Herpes simplex encephalitis may occur in patients carrying NF-κB essential modulator mutations, due to the impairment of NF-κB- and interferon regulatory factor 3-dependent-TLR3-mediated antiviral IFN production.
Keywords
NF-κBNuclear factor-κB essential modulatorX-linked recessiveSTAT-1EDA-IDHSENEMOTLRIKKTRAF3HSV-1SV40VSVMOIincontinentia pigmentiHerpes simplex encephalitisToll-like receptorCNScentral nervous systemnuclear factor-κBsignal transducer and activator of transcription 1Vesicular stomatitis virusSimian virus 40Herpes simplex virus-1multiplicity of infectionImmunodeficiencyToll-like receptor 3
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Magali PhD, Michael PhD, Kun MD, PhD, Aurelie MD, PhD, Huey-Hsuan PhD, Vanessa PhD, Lazaro Lorenzo, Tim MD, PhD, Janine MD, Xiao-Xia PhD, Alain PhD, Laurent MD, PhD, Jean-Laurent MD, PhD, Shen-Ying MD, PhD, Emmanuelle PhD, Anne PhD,