Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3198863 | Journal of Allergy and Clinical Immunology | 2011 | 14 Pages |
Abstract
These results indicate that the TRPM8 receptor is involved in cold-induced mucus hypersecretion through the Ca2+-PLC-PIP2-MARCKS signaling pathway.
Keywords
PSDNHBEMUC5ACTRPM8PKCMARCKSPLCPIP2IP3FVCInositol trisphosphateGFPTrpERKGAPDHshRNACa2+short hairpin RNAmyristoylated alanine-rich C kinase substratenormal human bronchial epithelialMucus hypersecretionCOPDChronic obstructive pulmonary diseaseendoplasmic reticulumBCTCforced vital capacityphosphatidylinositol 4,5-bisphosphatephospholipase Ctransient receptor potential melastatin 8Pleckstrin HomologyCold airtransient receptor potentialgreen fluorescent proteinProtein kinase Cextracellular signal-regulated kinaseglyceraldehyde-3-phosphate dehydrogenase
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Authors
MinChao PhD, Qi PhD, Gang PhD, Victor P. MD, PhD, Juliy M. MD, PhD, Xiang Dong MD, PhD,