| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3198913 | Journal of Allergy and Clinical Immunology | 2011 | 15 Pages |
Abstract
Our study implies that systemic immune activation might play a role in alteration of the normal epidermal phenotype, as suggested by the high correlation in expression of immune genes in ANL skin with the disease severity index.
Keywords
TGM1IVLMMP12EDCANLRT-PCRLCEcorneodesmosinCdsnFLGBSAMx1PCAReal-time PCRLORImmunohistochemistryIHCPrincipal component analysistransglutaminase 1Atopic dermatitisHARPbody surface areaDEGnonlesionalImmune activationfilaggrinLoricrinMatrix metalloproteinase 12Epidermal differentiation complexlate cornified envelopeDifferentially expressed geneinvolucrin
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Authors
Mayte PhD, Suzanne J. BS, Avner MD, Andrea MD, Kristine MD, Irma MSc, Shenghui MSc, Anne M. PhD, James G. MD, PhD, Emma MD, PhD,