Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3198974 | Journal of Allergy and Clinical Immunology | 2012 | 18 Pages |
Abstract
Our data demonstrate that IL-10 signaling in DCs is dispensable during naive T-cell priming but is critical to prevent an exaggerated effector T-cell response in the skin.
Keywords
Non-tgFOXP3FITCCHSIL-10 receptorIL-10RsCD40LMHCIIPD-LTregAPCnatural killerMHC class IIallophycocyaninContact hypersensitivityT-betDendritic cellLangerhans cellDendritic cellsLangerhans cellsNontransgenicT-box transcription factor phycoerythrinfluorescein isothiocyanatesoluble CD40 ligandRegulatory T Immune regulationknockoutConditional gene targetingforkhead box protein 3SkinLymph node
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Authors
Mathilde J.H. MSc, Junda M. PhD, Boris PhD, Björn E. PhD,