| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3199063 | Journal of Allergy and Clinical Immunology | 2011 | 17 Pages |
Abstract
Modifications in the 3-dimensional structure of Bet v 1.0101 resulted in a change of its immunologic properties. We observed that the fold alteration led to a modified crosstalk with dendritic cells and a shift of the immune response polarization toward a mixed TH1/TH2 cytokine production.
Keywords
DLSLimulus Amebocyte LysateFITCprotein remodelingIgE reactivityBMDCAPCRBLLALAllergenicityallophycocyaninAlumLysosomal degradationAntigen uptakeANSDendritic cellBone marrow–derived dendritic cellstimulation indexFTIRfluorescein isothiocyanateRat basophilic leukemiawild-typealuminum hydroxideDynamic Light Scattering
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Authors
Michael PhD, Michael PhD, Martin PhD, Nadja PhD, Sonja PhD, Andrea PhD, Claudia MSc, Ulrike MSc, Ronald PhD, Peter PhD, Josef PhD, Barbara PhD, Gernot PhD, Fatima PhD,