| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3199513 | Journal of Allergy and Clinical Immunology | 2010 | 18 Pages |
Abstract
Increased exposure to AAP is associated with hypermethylation of the Foxp3 locus, impairing Treg-cell function and increasing asthma morbidity. AAP could play a role in mediating epigenetic changes in Treg cells, which may worsen asthma by an immune mechanism.
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Authors
Kari MD, PhD, Cameron BA, Elizabeth M. PhD, Boriana MA, S. Katharine PhD, John MD, Ira MD, MPH,