Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
319958 | European Neuropsychopharmacology | 2007 | 4 Pages |
Abstract
Serotonergic neurotransmission has been implicated in suicidal behavior, including inconsistent results concerning the serotonin transporter promoter polymorphism (5-HTTLPR). Here, we analyzed the 5-HTTLPR in suicide attempters (n = 85). Comparing the presence of SS with SL + LL genotypes showed a significantly higher prevalence of the SS genotype in suicide attempters with high medical damage scores (χ2 = 9.054, df = 1, p = 0.0026). The results suggest that the S-allele may predispose for suicidal behavior characterized by high determination.
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Authors
Danuta Wasserman, Thomas Geijer, Marcus Sokolowski, Amos Frisch, Elena Michaelovsky, Abraham Weizman, Vsevolod Rozanov, Jerzy Wasserman,