| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3199607 | Journal of Allergy and Clinical Immunology | 2011 | 17 Pages |
Abstract
Gene expression profiling provides a novel means to investigate the molecular mechanisms and classifications of asthma phenotypes. There are 3 distinct transcriptional phenotypes of asthma that relate to both clinical and inflammatory parameters.
Keywords
ICSIRAK2IL1R2ALPLIL1RNFeNONF-κBACQFVCIL-1BCRqPCRQuantitative PCRIL-1 receptor antagonistEosinophilsfractional exhaled nitric oxidebody mass indexBMITAPforced vital capacityTNF-αnuclear factor-κBasthma phenotypesgene expression profilinginduced sputumNeutrophilsGene ontologyAsthma Control QuestionnairequartileInhaled corticosteroidB-cell receptor
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Authors
Katherine J. PhD, BBiomedSci (Hons), Jodie L. PhD, BSc (Hons), Lisa G. PhD, BSc (Hons), Rodney J. DSc, FRCPath, FHGSA, Peter G. MBBS, FRACP,