Invariant natural killer T cells from children with versus without food allergy exhibit differential responsiveness to milk-derived sphingomyelin

Article ID	Journal	Published Year	Pages	File Type
3199685	Journal of Allergy and Clinical Immunology	2011	21 Pages	PDF

Abstract

iNKTs from children with FA, especially those with MA, are reduced in number and exhibit a Th2 bias in response to Î±Gal and milk-sphingomyelin. These data suggest a potential role for iNKTs in FA.

Keywords

CFSE αGal iNKT phorbol 12-myristate 13-acetate APC TCr DMSO PMA invariant natural killer T cells α-galactosylceramide Cow’s milk allergy Food allergy antigen-presenting cell sphingolipids recombinant human CHOP Peripheral blood Dimethyl sulfoxide invariant natural killer T cell complete medium T-cell receptor

Related Topics

Life Sciences Immunology and Microbiology Immunology

Preview

Invariant natural killer T cells from children with versus without food allergy exhibit differential responsiveness to milk-derived sphingomyelin

Authors

Soma MD, Valsamma PhD, Jordan S. MD, PhD, Jonathan M. MD, PhD, Laura MD, Emily BS, Rushani MD, Kim E. MD, Antonella MD, PhD,