Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3199694 | Journal of Allergy and Clinical Immunology | 2011 | 18 Pages |
Abstract
We show that airway inflammation mediated by TH17 cells facilitates sensitization to new antigens and confers increased airway responsiveness in a murine model of polysensitization, suggesting a mechanism involving IL-17A behind the increased risk for allergic sensitization in polysensitized subjects.
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Authors
Melanie PhD, Hui-Chen PhD, Paula Preston-Hurlburt, Patricia Ranney, Heinz-Gerd PhD, Joachim PhD, Valérie MS, Christian MD, H. Kim PhD, Anna-Maria MD,