Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3199836 | Journal of Allergy and Clinical Immunology | 2011 | 11 Pages |
Abstract
Specificity protein 1 knockdown enhances viral replication in keratinocytes by downregulating gene expression of PKR and OAS2. Sp1 deficiency in ADEH+ patients may contribute to their increased propensity to disseminated skin viral infections. IFN-γ augmentation may be a potential treatment for ADEH+ patients.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Lianghua MD, PhD, Michael D. PhD, Byung Eui MD, PhD, Joanne E. BA, Clifton F. MS, Donald Y.M. MD, PhD,