| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3199890 | Journal of Allergy and Clinical Immunology | 2011 | 16 Pages |
Abstract
PBECs from asthmatic donors have a normal antiviral response to exogenous IFN-β. The ability of IFN-β to suppress viral replication suggests that it might limit virus-induced exacerbations by shortening the duration of the inflammatory response.
Keywords
qPCRPBECIRF-7TCID50IP-10RIG-IMDA-5PKRTLRBECSTATInnate immunityType I interferonsAsthma exacerbationToll-like receptorBronchial epithelial cellInterferon regulatory factor 7Signal transducer and activator of transcriptionquantitative real-time PCRInterferon-inducible protein 10melanoma differentiation-associated gene 5
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Authors
Julie A. PhD, Yunhe PhD, Chris PhD, Valia MD, Peter H. DM, Stephen T. DSc, Donna E. PhD,