Article ID Journal Published Year Pages File Type
3199903 Journal of Allergy and Clinical Immunology 2011 20 Pages PDF
Abstract
These data show that the C104R mutation and its murine equivalent, C76R, can significantly disrupt TACI function, probably through haploinsufficiency. Furthermore, the heterozygous C76R mutation alone is sufficient to disturb B-cell function with lymphoproliferation and immunoglobulin production defects.
Related Topics
Life Sciences Immunology and Microbiology Immunology
Authors
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