| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3199905 | Journal of Allergy and Clinical Immunology | 2011 | 16 Pages |
Abstract
These results suggest that autophagy is not essential for the development but plays a crucial role in degranulation of mast cells. Thus, autophagy might be a potential target to treat allergic diseases in which mast cells are critically involved.
Keywords
autophagy related genehigh affinity receptor for IgELC3-ICD63LTC4BMMCFcεRIM-CSFphorbol 12-myristate 13-acetateLC3-IISCFGM-CSFp62MFIGFPATGSNARELC3MVBSPMAPCASmall interfering RNAsiRNAPassive cutaneous anaphylaxisAutophagymultivesicular bodieslight chain 3Dendritic cellBone marrow–derived mast cellStem Cell FactorDegranulationLeukotriene C4Mast cellmacrophage colony-stimulating factorgranulocyte macrophage colony-stimulating factorbone marrowmean fluorescence intensityGreen fluorescence proteinPoly I:Cpolyinosinic-polycytidylic acid
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Authors
Hiroko PhD, Takashi PhD, Yuko PhD, Masaaki PhD, Satoshi PhD, Akitsugu PhD, Yoshinobu PhD, Junji PhD, Keigo PhD, Sachiko BD, François PhD, Tetsuro PhD, Toru DDS, MD, PhD, Eiki MD, PhD, Hideoki MD, PhD, Ko MD, PhD, Hiroyasu MD, PhD,