Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3200080 | Journal of Allergy and Clinical Immunology | 2010 | 12 Pages |
Abstract
Nitroso sulfonamide metabolites form potent antigenic determinants for T cells from hypersensitive patients. T-cell responses against drugs (metabolites) bound directly to MHC or MHC/peptide complexes can occur through cross-reactivity with the haptenic immunogen.
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Authors
J. Luis BSc, Neil PhD, Sabah BSc, Basil PhD, Werner J. MD, B. Kevin PhD, Dean J. PhD,