Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3200450 | Journal of Allergy and Clinical Immunology | 2009 | 15 Pages |
Abstract
Acute asthma attacks are associated with hypersecretion of EGF and amphiregulin in the airway. Recurrent acute attacks may aggravate airway remodeling.
Keywords
HB-EGFbSMCMucin 5ACNHBEMUC5ACEGFRERKEGFBronchial asthmaamphiregulinAliTissue remodelingNormal human bronchial epithelial cellsBronchial epithelial cellsepidermal growth factorHeparin-binding epidermal growth factor–like growth factorMast cellsair-liquid Interfaceextracellular signal-regulated kinaseEpidermal growth factor receptor
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Authors
Yukinori BSc, Kanami PhD, Tetsuya MD, Akio PhD, Yasuhiro MD, PhD, Hirohisa MD, PhD, Chisei MD, PhD, Yoshimichi MD, PhD,