Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3200827 | Journal of Allergy and Clinical Immunology | 2010 | 15 Pages |
Abstract
Our findings provide a mechanism whereby PAF mediates an amplification loop for MC activation in the generation of anaphylaxis.
Keywords
PKCMrgX2Iscove modified Dulbecco mediumIMDMPAI-1PTXPLCGPCRshRNAGAPDHG protein–coupled receptorshort hairpin RNAAnaphylaxisPeripheral bloodpertussis toxinPlatelet-activating factorphospholipase CMast cellplasminogen activator inhibitor 1PAFHistamineProtein kinase Cprostaglandinglyceraldehyde-3-phosphate dehydrogenaseplatelet-activating factor receptor
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Authors
Naoki PhD, Tomomi BSc, Peter DM, Glenn PhD, Hironori MD, PhD, Kazumitsu MD, PhD, Hirohisa MD, PhD, Chisei MD, PhD, Yoshimichi MD, PhD,