Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3200932 | Journal of Allergy and Clinical Immunology | 2009 | 17 Pages |
Abstract
FLG deficiency alone provokes a paracellular barrier abnormality in mice that reduces inflammatory thresholds to topical irritants/haptens, likely accounting for enhanced antigen penetration in FLG-associated AD.
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Authors
Tiffany C. MD, Mao-Qiang MD, Yutaka MD, Debra Crumrine, Roshan MD, John P. DVM, PhD, Kathleen A. BS, Theodora M. MD, Melanie BS, Soyun MD, PhD, Yan MD, Anna PhD, Matthias MD, Kenneth R. MD, Peter M. MD,