Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3201013 | Journal of Allergy and Clinical Immunology | 2008 | 8 Pages |
Abstract
Our data show that CysLTs acting through CysLTR1 can significantly influence the activation and migration of human monocytes and that these effects can be fully inhibited by CysLTR1 antagonists.
Keywords
Cysteinyl leukotrieneEGTACysLTEGRCysteinyl leukotrienesERKHUVECIP3CysLTR1inositol-1,4,5-triphosphateMAPKEthyleneglycol-bis-(β-aminoethylether)-N,N,N′,N′-tetraacetic acidHuman monocytesHuman umbilical vein endothelial cellnuclear factorFosBLeukotrieneearly growth responsemitogen-activated protein kinaseImmediate-early genesChemotaxisextracellular signal-regulated kinase
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Authors
Grzegorz MD, PhD, Li-Yuan PhD, Sahrudaya MS, Steven BS, Jennifer MS, Peter J. PhD, Carolea MS, Robert L. MD, James H. MD,