| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3201081 | Journal of Allergy and Clinical Immunology | 2009 | 11 Pages |
Abstract
Lung CD11bhighCD103-SIRP-α+ DC migration is governed by self-CD47 expression, and manipulation of the CD47/SIRP-α pathway suppresses CD103-SIRP-α+ DC-driven pathogenic TH2 responses and airway inflammation.
Keywords
FOXP3SIRPTh2BMDCMLNCD103PDCCD47MFIFITCAllergic inflammationBALFDendritic cellPlasmacytoid dendritic cellBone marrow–derived dendritic cellDendritic cellsfluorescein isothiocyanateBronchoalveolar lavage fluidMigrationmean fluorescence intensitySignal regulatory proteinforkhead box protein 3Mediastinal lymph nodeLymph node
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Authors
Marianne MSc, Manuel BSc, Geneviève BSc, Karim Hamdy BSc, Hamida PhD, Bart N. MD, PhD, Marika MD, PhD,