Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3201130 | Journal of Allergy and Clinical Immunology | 2009 | 8 Pages |
Abstract
There is a bidirectional association between severe RSV infection and asthma. Severe RSV infection is associated with a short-term increase in the risk of subsequent asthma, suggesting that RSV induce bronchial hyperresponsiveness; and asthma is associated with a long-term increased susceptibility for severe RSV disease, suggesting a host factor being responsible for the severe response to RSV infection. This suggests that severe RSV infection and asthma may share a common genetic predisposition and/or environmental exposure.
Keywords
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Immunology
Authors
Lone Graff MD, PhD, Jacob MSc, Simon Francis MD, PhD, Anne-Marie MSc, Susan MSc, Peter DMSci, Kirsten Ohm MD, PhD, Axel MSc, PhD, Vibeke MD, DMSci, Hans MD, DMSci,