| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3201132 | Journal of Allergy and Clinical Immunology | 2009 | 15 Pages |
Abstract
Children with severe asthma have increased biomarkers of oxidant stress in the ELF that are associated with increased formation of GSSG and a shift in the GSH redox potential toward the more oxidized state.
Keywords
FeNOICSELFBALGSHGSTFVCGPXCDNBGSSG1-chloro-2,4-dinitrobenzene8-isoprostanesHydrogen peroxideAsthmaAirway obstructionOxidative stressFraction of exhaled nitric oxideforced vital capacitybronchoalveolar lavagemalondialdehydeEpithelial lining fluidRedox potentialChildrenInhaled corticosteroidGlutathioneglutathione (reduced form)glutathione S-transferaseoxidized glutathioneglutathione reductaseglutathione peroxidase
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Authors
Anne M. PhD, W. Gerald MD, Fernando MD, Mary PhD, Lou Ann S. PhD, Severe Asthma Research Program Severe Asthma Research Program,