| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3201144 | Journal of Allergy and Clinical Immunology | 2009 | 11 Pages |
Abstract
Perturbation of TLR-7 on naive human B cells can lead to the induction of immunoglobulin class switch and IgG production in the absence of B-cell receptor cross-linking and CD40-CD40L interaction. The results are relevant to vaccine development and mechanisms by which microbial infection may lead to autoimmunity.
Keywords
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Authors
Mark C. MD, PhD, Shilpi MD, Decheng MD, Yi MD, Amy L. BS, MS, C. Hank BA, MCI, Arnold I. MD,