Clinical efficacy and immune regulation with peanut oral immunotherapy

Article ID	Journal	Published Year	Pages	File Type
3201532	Journal of Allergy and Clinical Immunology	2009	106 Pages	PDF

Abstract

Oral immunotherapy induces clinical desensitization to peanut, with significant longer-term humoral and cellular changes. Microarray data suggest a novel role for apoptosis in OIT.

Keywords

FOXP3 Facilitated allergen binding IL-5 Treg OFC IL-10 SPT IgE MIP PBMC IgG immunotherapy oral immunotherapy immune tolerance Skin prick test Peanut hypersensitivity Apoptosis OIT Regulatory T cell Peripheral blood mononuclear cell Fab macrophage inflammatory protein forkhead box protein 3 Oral food challenge

Related Topics

Life Sciences Immunology and Microbiology Immunology

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Clinical efficacy and immune regulation with peanut oral immunotherapy

Authors

Stacie M. MD, Laurent PhD, Joseph L. MD, PhD, Amy M. MD, Tamara T. MD, Mike PhD, Wayne G. MD, PhD, Pamela CPNP, Karen A. RN, Margaret MD, James M. PhD, Stephen MD, Brian P. MD, Xiaoping MD, PhD, A. Wesley MD,