Roles of arginase variants, atopy, and ozone in childhood asthma

Article ID	Journal	Published Year	Pages	File Type
3202278	Journal of Allergy and Clinical Immunology	2009	15 Pages	PDF

Abstract

ARG1 and ARG2 loci are associated with childhood asthma. The association between ARG1 variation and asthma might depend on atopy and ambient ozone levels.

Keywords

AHR Arg2 PM2.5 PM10 ARG1 CHS MAF NOS Atopy Air pollution Nitrosative stress gene-environment interaction nuclear factor minor allele frequency principal component odds ratio Nitrogen dioxide NO2 Nitric oxide nitric oxide synthase Airway hyperresponsiveness Single nucleotide polymorphism SNP asthma genetics