Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3202550 | Journal of Allergy and Clinical Immunology | 2006 | 6 Pages |
Abstract
Eosinophilic esophagitis (EE) is a recently recognized disorder characterized by the accumulation of eosinophils in the esophagus. Symptoms of EE frequently mimic those of gastroesophageal reflux disease, but the 2 diseases are quite distinct in terms of the histopathology and response to therapy. We demonstrate that EE involves the interplay of numerous genes, especially the eosinophil chemoattractant eotaxin-3, allowing molecular distinction from other forms of esophagitis and consideration of targeted therapeutic intervention.
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Authors
Carine Blanchard, Ning Wang, Marc E. Rothenberg,