Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3207972 | Journal of the American Academy of Dermatology | 2009 | 21 Pages |
Abstract
This meta-analysis confirms the safety and tolerability of onabotulinumtoxinA for glabellar and lateral canthal lines, at the doses studied, based on the most comprehensive controlled safety analysis of onabotulinumtoxinA performed to date. The AEs observed were generally mild to moderate; most treatment-related AEs were related either to physical injection of product or local pharmacologic effects. Even with the increased statistical power of a large sample size, no new onabotulinumtoxinA-associated AEs emerged.
Keywords
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Dermatology
Authors
Mitchell F. MD, Terry I. MS, Janice M. PhD, Lynn M. MPH, George MD, Yasunori MD, PhD, Juanhong MS, Nina MBA, Beta L. MS,