Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3208700 | Journal of the American Academy of Dermatology | 2010 | 8 Pages |
Abstract
Cutaneous T-cell lymphomas most commonly have a CD4+ memory T-cell phenotype with relatively indolent course, but may in rare cases present with a CD8+ cytotoxic phenotype exhibiting strikingly more aggressive clinical behavior. We present two cases of the clinically aggressive subtype of primary cutaneous epidermotropic CD8+ cutaneous T-cell lymphoma and review the current literature, clinical behavior, and recommendations for treatment distinct from that of more common CD4+ variants of cutaneous T-cell lymphoma.
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Authors
Rachel H. Gormley, Stephen D. Hess, Dipti Anand, Jacqueline Junkins-Hopkins, Alain H. Rook, Ellen J. Kim,