| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3209229 | Journal of the American Academy of Dermatology | 2009 | 8 Pages |
BackgroundPalmoplantar psoriasis is associated with significant quality-of-life issues. Its epidemiology and phenotypical expression remain ill defined.ObjectiveWe reviewed the literature and our clinical experience and developed a new quality-of-life assessment tool.MethodsWe conducted a retrospective review of 150 patients with palmoplantar psoriasis.ResultsIn all, 78 (52%) patients displayed predominantly hyperkeratotic palmoplantar lesions, 24 (16%) pustular, 18 (12%) combination, and 30 (20%) had an indeterminate phenotype. In 27 (18%) patients, lesions were confined to the palms and soles. A new quality-of-life index was constructed to characterize disease severity. In all, 27 (18%) had mild, 72 (48%) moderate, and 51 (34%) severe disease involvement. Palmoplantar disease severity appeared independent from the degree of body surface area involvement.LimitationsThis was a retrospective review. The quality-of-life index remains to be statistically verified in prospective clinical studies.ConclusionDefining morphologic subtypes together with the use of a specific quality-of-life assessment tool in patients with palmoplantar psoriasis will improve our understanding and treatment of this recalcitrant form of psoriasis.
