Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3209738 | Journal of the American Academy of Dermatology | 2009 | 5 Pages |
Abstract
Long-term prognosis for advanced stages of cutaneous T-cell lymphoma may be beneficially altered with the use of multimodality therapy. However, refractory disease exists in which current therapeutic options fail to halt the progression of disease. We present 3 cases of refractory Sézary syndrome in which the combination of vorinostat and interferon gamma was well tolerated and produced significant clinical improvement. The potential immunologic basis for this is discussed.
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Authors
Jennifer M. Gardner, Camille E. Introcaso, Sunita D. Nasta, Ellen J. Kim, Carmela C. Vittorio, Alain H. Rook,