Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3211405 | Journal of the American Academy of Dermatology | 2006 | 4 Pages |
Abstract
We describe the case of a 13-year-old boy with stage I hypopigmented mycosis fungoides in whom minimal residual disease was detected with T-cell receptor γ-polymerase chain reaction after the disease was in complete clinical remission. We further cloned and sequenced the T-cell receptor γ-polymerase chain reaction product of the lesion in remission and found that the original T-cell clone still existed in decreased amounts. The patient was followed up for 3 1/2 years without any new lesions developing. The clinical significance of this residual malignant T-cell clone in mycosis fungoides remains to be elucidated.
Keywords
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Dermatology
Authors
Pa-Fan Hsiao, Cheng-Hsiang Hsiao, Tsen-Fang Tsai, Shiou-Hwa Jee,