Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3213693 | Journal of Dermatological Science | 2010 | 9 Pages |
Abstract
Our findings suggest that the ZAR1 intra-genic differentially methylated region would be a useful tumor marker for malignant melanoma and may be other type of cancers. The involvement of ZAR1 in the carcinogenesis of melanoma, still remains unclear, although we have examined tumorigenic capacities by exogenous full-length ZAR1 over-expression and siRNA knock-down experiments.
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Authors
Yui Shinojima, Tadashi Terui, Hiroyuki Hara, Makoto Kimura, Jun Igarashi, Xiaofei Wang, Hiroyuki Kawashima, Yujin Kobayashi, Satomi Muroi, Satoshi Hayakawa, Mariko Esumi, Kyoko Fujiwara, Srimoyee Ghosh, Tatsuo Yamamoto, William Held, Hiroki Nagase,