| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3214087 | Journal of Dermatological Science | 2009 | 7 Pages |
Abstract
MicroRNAs (miRNAs) are very small endogenous RNA molecules about 22–25 nucleotides in length, capable of post-transcriptional gene regulation. miRNAs bind to their target messenger RNAs (mRNAs), leading to cleavage or suppression of target mRNA translation based on the degree of complementarity. miRNAs have recently been shown to play pivotal roles in diverse developmental and cellular processes and linked to a variety of skin diseases and cancers. Disruption of miRNA metabolism is also involved in wound healing and inflammatory skin conditions. Here, we review the role of miRNAs in cutaneous biology.
Related Topics
Health Sciences
Medicine and Dentistry
Dermatology
Authors
Michael Sand, Thilo Gambichler, Daniel Sand, Marina Skrygan, Peter Altmeyer, Falk G. Bechara,