| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3215404 | Journal of Investigative Dermatology | 2013 | 4 Pages |
Abstract
A pathogenic crosstalk between epithelial and immune cells underpins the aberrant immune and epidermal responses seen in psoriasis. Data from a novel mouse model of psoriasiform skin inflammation not only highlight the importance of the interplay between keratinocytes, targets of genetic manipulation, and T cells as the major effector cells, but also reveal a critical role for CD8 T cells and IFN-γ in disease initiation.
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Authors
Paola Di Meglio, João H. Duarte,