| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3217201 | Journal of Investigative Dermatology | 2006 | 4 Pages |
Abstract
Yanagihori et al. found an HLA-independent higher frequency of IL-12B promoter polymorphism in Adamantiades–Behçet's disease (ABD) patients than in controls. Stimulation with streptococcal antigens specifically increased expression of patients' peripheral blood mononuclear cells IL-12 p40/p70. The authors provide evidence for an antibacterial host response toward T-helper type 1 immunity mediated by IL-12 in patients with ABD, which is HLA independent.
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Authors
Christos C. Zouboulis,