Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3217975 | Journal of Investigative Dermatology | 2008 | 4 Pages |
Abstract
Notch signaling is an evolutionally conserved pathway that serves as a critical regulator of cell fate. From a series of studies, including a report in this issue, researchers have begun to elucidate the critical functions of Notch signaling in the regulation of melanocyte lineage development. With evidence of a recently identified role for Notch signaling in melanomagenesis, characterization of downstream molecular events may offer potential avenues for the development of novel therapeutic strategies.
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Authors
Masatake Osawa, David E. Fisher,