| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3218100 | Journal of Investigative Dermatology | 2007 | 4 Pages |
Abstract
Merkel cell carcinoma (MCC) is a neuroendocrine skin cancer with a rising incidence (1500 U.S. cases per year) that now exceeds that of cutaneous T-cell lymphoma and a mortality (33%) exceeding that of melanoma. Despite this impact, little is known about its biology. Recent studies have shown that Ras/MAP kinase activity is absent and possibly detrimental to this cancer. This makes MCC distinct from other UV-induced skin cancers and highlights the question of what drives this malignancy.
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Authors
Bianca Lemos, Paul Nghiem,