| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3218796 | Journal of Investigative Dermatology | 2006 | 4 Pages |
Abstract
Dendritic cells are the coordinators of the adaptive immune response. Chronic activation of skin dendritic cells by keratinocyte expression of CD40 ligand (CD40L; CD154) leads to autoimmunity. In this issue, systemic administration of tacrolimus is shown by Loser et al. to effectively treat autoimmunity in a murine model involving transgenic keratinocyte expression of CD40L.
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Authors
Jan P. Dutz,