Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3233859 | Annals of Emergency Medicine | 2006 | 4 Pages |
Abstract
Methadone overdoses are increasing in parallel with the increased frequency of opiate substitution therapy in adults. Although unintentional methadone intoxication in children is rare, it is becoming more frequently recognized. We report 3 cases of unintentional methadone overdose in toddlers who initially displayed central nervous system depression associated with severe nonketotic hyperglycemia and discuss the possible pathophysiologic mechanisms of an underrecognized symptom of opiate intoxication in young children.
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Authors
Sinan Tiras, Vincent Haas, Laurent Chevret, Marion Decobert, Anne Buisine, Denis Devictor, Philippe Durand, Pierre Tissières,