Massive Transfusion: Where are We Now?

Major hemorrhage is a leading cause of mortality world over. Counteracting severe blood loss usually requires transfusion of a large number of blood units, qualifying as massive transfusion more often than not. Concepts in massive transfusion have undergone substantial changes in the past years not just with acquisition of new knowledge on this subject but with technical advances in component preparation. We aim at providing an overview of the changing trends and concepts in management of massive blood loss.