Primary Sarcoma of the Prostate and Thrombocythemia in Adult; A First Case Report in English Literature

Sarcoma is an unusual type of prostate cancer in adult. Prostate sarcoma (PS) is rare with only 183 cases reported in the English language medical literature from 1938-1998. Here we present a case of african.national who presented with locally advanced prostate sarcoma with thrombocythemia. However responded favourably to his initial trearment. He was treated with anthracycline based systemic chemotherapy; monoclonal antibody/large molecular target therapy (cyclophosphamide, liposomal adriamycin, vincristine, Cetuximab) for first three months without grade 3 or 4 toxicity. Then given synchronous chemo-target-radiation therapy in view of favourable initial radiological response and clinical benefit (effective palliation in terms of pain control and bleeding control).