Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3236167 | Clinical Pediatric Emergency Medicine | 2008 | 13 Pages |
Abstract
Beta-adrenergic blocking agents or β-blockers are prescribed for the treatment of a broad array of common disorders. Their widespread use, coupled with a narrow therapeutic index, contributes to their being a significant cause of poisoning from overdose and the second most common cause of mortality from cardiovascular agents. This article provides an overview of beta-adrenergic system pathophysiology and the properties and pharmacokinetics of β-blockers. Also discussed are the various effects and management of β-blockers in overdose settings.
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Authors
Angela C. Anderson,