Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3237499 | Emergency Medicine Clinics of North America | 2007 | 23 Pages |
Abstract
State-of-the-art therapy for β-adrenergic receptor blocker and calcium channel antagonist toxicity is reviewed in the light of new insights into drug-induced shock. A brief discussion of pathophysiology, including cardiac, hemodynamic, and metabolic effects of cardiac drug toxicity, provides a foundation for understanding the basis of therapy. The major focus of this review is a critical evaluation of antidotal use of calcium, glucagon, catecholamines, insulin-euglycemia, and other novel therapies based on investigational studies and cumulative clinical experience.
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Authors
William Kerns II,