Liposclerosing myxofibrous tumor: A series of 9 cases and review of the literature

BackgroundLiposclerosing myxofibrous primary bone tumor is a rare benign bone lesion that was characterized by complex mixture of various histological elements.MethodsWe have studied the radiological, clinical and pathological features of nine patients with this disorder. Pain and limping were the main symptoms.ResultsRadiographic images typically showed a geographic lytic lesion with thick sclerotic margin, reflecting a pattern of slow growth. Histological sections revealed a polymorphic neoplasia characterized by predominant proliferation of stellate and fusiform cells aimed the myxoid matrix.ConclusionsThese features suggest that the lesion may represent a variant of fibrous dysplasia with a high risk of malignant transformation.