Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
325196 | Journal of the American Academy of Child & Adolescent Psychiatry | 2014 | 18 Pages |
Abstract
Our findings support theories of atypical FSTC maturation in pediatric OCD by providing the first evidence for altered trajectories of white matter development in anterior corpus callosum, anterior cingulum bundle, and ALIC in young patients. Steeper age-related increases of FA in these and other select white matter tracts in OCD, compared to those in healthy controls, may derive from an early delay in white matter development and/or prolonged white matter growth; however, confirmation of these possibilities awaits longitudinal work.
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Authors
Kate D. MD, Yanni PhD, Elyse N. BS, Stephan F. MD, Robert C. PhD,