Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
325346 | Journal of the American Academy of Child & Adolescent Psychiatry | 2013 | 10 Pages |
Abstract
Having removed a previously identified 18.7% of HR siblings with ASD outcomes from all analyses, HR siblings nevertheless exhibited higher mean levels of ASD severity and lower levels of developmental functioning than LR children. However, the latent class membership of four-fifths of the HR siblings was not significantly different from that of LR control subjects. One-fifth of HR siblings belonged to classes characterized by higher ASD severity and/or lower levels of developmental functioning. This empirically derived characterization of an early-emerging pattern of difficulties in a minority of 3-year-old HR siblings suggests the importance of developmental surveillance and early intervention for these children.
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Authors
Daniel Ph.D., Gregory S. Ph.D., Sally Ph.D., Karen Ph.D., Alice Ph.D., Lonnie M.D., F.R.C.P.C., Rebecca J. Ph.D., Tony Ph.D., Wendy L. Ph.D., John N. M.D., Ted Ph.D., Leslie J. Ph.D., Susan Ph.D., Jana M. Ph.D., Mark S. Ph.D., Sally J. Ph.D.,