Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3272228 | Journal de Gynécologie Obstétrique et Biologie de la Reproduction | 2015 | 16 Pages |
Abstract
The prescription of calcium channel blockers as tocolysis exposes patients to maternal side effects, which are not serious most of the time, and less frequent than with the β-agonist. Severe maternal complications were nonetheless reported more frequently with Nicardipine than Nifedipine, which justifies avoiding Nicardipine in tocolysis. Nifedipine is the most studied molecule. It is not possible to define a maximum posology from literature data. It seems unreasonable to associate different tocolytics and necessary to closely monitor maternal blood pressure, the occurrence of a skin reaction or hypersensitivity, dyspnea or chest pain during treatment.
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Authors
E. Clouqueur, S. Gautier, P. Vaast, C. Coulon, P. Deruelle, D. Subtil, V. Debarge,