Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3272947 | Journal de Gynécologie Obstétrique et Biologie de la Reproduction | 2010 | 5 Pages |
Abstract
Perfused human placental lobule was developed during the 1970s. Only this model respects the anatomical features of the human placenta. This approach allows different technical conditions (concentrations of drugsâ¦) without ethical problems. Limitations of this ex vivo model are detailed in this review, also its recent contributions in better understanding of placental passage of drugs.
Keywords
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Authors
P.-F. Ceccaldi, L. Mandelbrot, R. Farinotti, F. Forestier, S. Gil,