Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3273304 | Journal de Gynécologie Obstétrique et Biologie de la Reproduction | 2009 | 5 Pages |
Abstract
Tamoxifen is widely used in the breast cancer treatment. Its side effects on the endometrium are well-known, but more and more worse prognosis uterine sarcoma are described. Based on recent literature review, the cause and effect chain between tamoxifen and uterine sarcoma is argued, which confirms that a risk exists as from 2Â years of treatment, a cumulative dose of 15Â g, and that malignant mixed mesodermal tumours appear to be the most frequent.
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Authors
L. Homer, M. Muller, P.-F. Dupré, B. Lucas, O. Pradier,