| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3274216 | Médecine des Maladies Métaboliques | 2015 | 6 Pages |
Abstract
Metabolic surgery is an operative manipulation ofa normal organ to achieve a healthy biological result. The first step of metabolic surgery was represented by partial ileal bypass which was the intervention modality for the first affirmative lipid atheroscle-rosis trial. However the marked lowering LDL-cholesterol induced by this procedure was not clinically pertinent after the arrival of statins. Now metabolic surgery is under question in the field of type 2 diabetes (T2D). Precocious diabetes remissions were frequently reported after bariatric surgery especially gastric bypass. The fact that glucose homeostasis was achieved with a weight-loss independent mechanism has led to the paradigm that T2D may be a surgical disease. The reasons of this dramatically improvement in diabetes after surgery are now under evaluation.
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Authors
J.-L. Schlienger,